GPR180-GPC6 Fusion FISH Probe
The GPR180-GPC6 Fusion FISH Probe is used to confirm a fusion of the GPR180 and GPC6 genes. The fusion of the GPR180 and GPC6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPR180-GPC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-RERE | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-REOR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-REGO | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-REGR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-REAQ | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-ORRE | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-OROR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-ORGO | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GORE | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GOOR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GOGO | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GOGR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GRRE | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GROR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GRGO | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GRGR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-AQRE | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-AQOR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-AQGO | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-AQGR | 20 (40 μL) | 200 μL |
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| GPR180-GPC6-20-AQAQ | 20 (40 μL) | 200 μL |
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GPC6 Gene Summary
The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1. [provided by RefSeq, Nov 2016]
Gene Name: Glypican 6
Chromosome: CHR13: 93879077 -95060273
Locus: 13q31.3-q32.1
GPR180 Gene Summary
This gene encodes a protein that is a member of the G protein-coupled receptor superfamily. This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling. [provided by RefSeq, Jul 2008]
Gene Name: G Protein-coupled Receptor 180
Chromosome: CHR13: 95254103 -95286899
Locus: 13q32.1
Gene Diseases
The GPR180 GPC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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