GPHN-PRKD1 Fusion FISH Probe
The GPHN-PRKD1 Fusion FISH Probe is used to confirm a fusion of the GPHN and PRKD1 genes. The fusion of the GPHN and PRKD1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPHN-PRKD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-RERE | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-REOR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-REGO | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-REGR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-REAQ | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-ORRE | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-OROR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-ORGO | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GORE | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GOOR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GOGO | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GOGR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GRRE | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GROR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GRGO | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GRGR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-AQRE | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-AQOR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-AQGO | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-AQGR | 20 (40 μL) | 200 μL |
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| GPHN-PRKD1-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKD1 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulation of cell shape and adhesion. [provided by RefSeq, Jan 2017]
Gene Name: Protein Kinase D1
Chromosome: CHR14: 30045686 -30396899
Locus: 14q12
GPHN Gene Summary
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
Gene Name: Gephyrin
Chromosome: CHR14: 66974124 -67648525
Locus: 14q23.3-q24.1
Gene Diseases
The GPHN PRKD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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