GOLGA5-RIN3 Fusion FISH Probe
The GOLGA5-RIN3 Fusion FISH Probe is used to confirm a fusion of the GOLGA5 and RIN3 genes. The fusion of the GOLGA5 and RIN3 genes has been associated with Lung Adenocarcinoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GOLGA5-RIN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-RERE | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-REOR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-REGO | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-REGR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-REAQ | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-ORRE | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-OROR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-ORGO | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GORE | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GOOR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GOGO | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GOGR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GRRE | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GROR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GRGO | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GRGR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-AQRE | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-AQOR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-AQGO | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-AQGR | 20 (40 μL) | 200 μL |
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| GOLGA5-RIN3-20-AQAQ | 20 (40 μL) | 200 μL |
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GOLGA5 Gene Summary
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. A pseudogene of this gene is located on the short arm of chromosome 5. [provided by RefSeq, Jul 2013]
Gene Name: Golgin A5
Chromosome: CHR14: 93260649 -93306304
Locus: 14q32.12
RIN3 Gene Summary
Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Ras And Rab Interactor 3
Chromosome: CHR14: 92980124 -93155334
Locus: 14q32.12
Gene Diseases
The GOLGA5 RIN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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