GNG7-PSMD1 Fusion FISH Probe
The GNG7-PSMD1 Fusion FISH Probe is used to confirm a fusion of the GNG7 and PSMD1 genes. The fusion of the GNG7 and PSMD1 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNG7-PSMD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-RERE | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-REOR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-REGO | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-REGR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-REAQ | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-ORRE | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-OROR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-ORGO | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GORE | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GOOR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GOGO | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GOGR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GRRE | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GROR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GRGO | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GRGR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-AQRE | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-AQOR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-AQGO | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-AQGR | 20 (40 μL) | 200 μL |
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| GNG7-PSMD1-20-AQAQ | 20 (40 μL) | 200 μL |
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GNG7 Gene Summary
The G Protein Subunit Gamma 7 (GNG7) gene is located on chr19 :2511217-2702746 at 19p13.3.
Gene Name: G Protein Subunit Gamma 7
Chromosome: CHR19: 2511217 -2702746
Locus: 19p13.3
PSMD1 Gene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2010]
Gene Name: Proteasome 26S Subunit, Non-ATPase 1
Chromosome: CHR2: 231921577 -232037540
Locus: 2q37.1
Gene Diseases
The GNG7 PSMD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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