GNB2L1-APOB Fusion FISH Probe
The GNB2L1-APOB Fusion FISH Probe is used to confirm a fusion of the GNB2L1 and APOB genes. The fusion of the GNB2L1 and APOB genes has been associated with Liver Hepatocellular Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNB2L1-APOB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-RERE | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-REOR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-REGO | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-REGR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-REAQ | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-ORRE | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-OROR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-ORGO | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-ORAQ | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GORE | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GOOR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GOGO | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GOGR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GOAQ | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GRRE | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GROR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GRGO | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GRGR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-GRAQ | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-AQRE | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-AQOR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-AQGO | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-AQGR | 20 (40 μL) | 200 μL |
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| GNB2L1-APOB-20-AQAQ | 20 (40 μL) | 200 μL |
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APOB Gene Summary
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Gene Name: Apolipoprotein B
Chromosome: CHR2: 21224300 -21266945
Locus: 2p24.1
Gene Diseases
The GNB2L1 APOB Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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