GNA13-NR3C1 Fusion FISH Probe
The GNA13-NR3C1 Fusion FISH Probe is used to confirm a fusion of the GNA13 and NR3C1 genes. The fusion of the GNA13 and NR3C1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNA13-NR3C1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-RERE | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-REOR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-REGO | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-REGR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-REAQ | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-ORRE | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-OROR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-ORGO | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GORE | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GOOR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GOGO | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GOGR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GRRE | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GROR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GRGO | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GRGR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-AQRE | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-AQOR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-AQGO | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-AQGR | 20 (40 μL) | 200 μL |
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| GNA13-NR3C1-20-AQAQ | 20 (40 μL) | 200 μL |
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NR3C1 Gene Summary
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
Gene Name: Nuclear Receptor Subfamily 3 Group C Member 1
Chromosome: CHR5: 142657495 -142815077
Locus: 5q31.3
GNA13 Gene Summary
The G Protein Subunit Alpha 13 (GNA13) gene is located on chr17 :63005406-63052920 at 17q24.1.
Gene Name: G Protein Subunit Alpha 13
Chromosome: CHR17: 63005406 -63052920
Locus: 17q24.1
Gene Diseases
The GNA13 NR3C1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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