GNA12-AMACR Fusion FISH Probe
The GNA12-AMACR Fusion FISH Probe is used to confirm a fusion of the GNA12 and AMACR genes. The fusion of the GNA12 and AMACR genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNA12-AMACR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-RERE | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-REOR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-REGO | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-REGR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-REAQ | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-ORRE | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-OROR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-ORGO | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-ORAQ | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GORE | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GOOR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GOGO | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GOGR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GOAQ | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GRRE | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GROR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GRGO | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GRGR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-GRAQ | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-AQRE | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-AQOR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-AQGO | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-AQGR | 20 (40 μL) | 200 μL |
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| GNA12-AMACR-20-AQAQ | 20 (40 μL) | 200 μL |
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GNA12 Gene Summary
The G Protein Subunit Alpha 12 (GNA12) gene is located on chr7 :2767740-2883959 at 7p22.3-p22.2.
Gene Name: G Protein Subunit Alpha 12
Chromosome: CHR7: 2767740 -2883959
Locus: 7p22.3-p22.2
AMACR Gene Summary
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
Gene Name: Alpha-methylacyl-CoA Racemase
Chromosome: CHR5: 33987090 -34008220
Locus: 5p13.2
Gene Diseases
The GNA12 AMACR Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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