GLUL-UNC13A Fusion FISH Probe
The GLUL-UNC13A Fusion FISH Probe is used to confirm a fusion of the GLUL and UNC13A genes. The fusion of the GLUL and UNC13A genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLUL-UNC13A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-RERE | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-REOR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-REGO | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-REGR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-REAQ | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-ORRE | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-OROR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-ORGO | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GORE | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GOOR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GOGO | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GOGR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GRRE | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GROR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GRGO | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GRGR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-AQRE | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-AQOR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-AQGO | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-AQGR | 20 (40 μL) | 200 μL |
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| GLUL-UNC13A-20-AQAQ | 20 (40 μL) | 200 μL |
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GLUL Gene Summary
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Glutamate-ammonia Ligase
Chromosome: CHR1: 182350838 -182361341
Locus: 1q25.3
UNC13A Gene Summary
This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Feb 2012]
Gene Name: Unc-13 Homolog A
Chromosome: CHR19: 17712136 -17799008
Locus: 19p13.11
Gene Diseases
The GLUL UNC13A Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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