GLUL-EIF2AK2 Fusion FISH Probe
The GLUL-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the GLUL and EIF2AK2 genes. The fusion of the GLUL and EIF2AK2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLUL-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| GLUL-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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GLUL Gene Summary
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Glutamate-ammonia Ligase
Chromosome: CHR1: 182350838 -182361341
Locus: 1q25.3
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The GLUL EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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