GLUL-DDX27 Fusion FISH Probe
The GLUL-DDX27 Fusion FISH Probe is used to confirm a fusion of the GLUL and DDX27 genes. The fusion of the GLUL and DDX27 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLUL-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| GLUL-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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GLUL Gene Summary
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Glutamate-ammonia Ligase
Chromosome: CHR1: 182350838 -182361341
Locus: 1q25.3
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The GLUL DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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