GLRX3-SGMS1 Fusion FISH Probe
The GLRX3-SGMS1 Fusion FISH Probe is used to confirm a fusion of the GLRX3 and SGMS1 genes. The fusion of the GLRX3 and SGMS1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLRX3-SGMS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-RERE | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-REOR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-REGO | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-REGR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-REAQ | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-ORRE | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-OROR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-ORGO | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GORE | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GOOR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GOGO | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GOGR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GRRE | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GROR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GRGO | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GRGR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-AQRE | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-AQOR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-AQGO | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-AQGR | 20 (40 μL) | 200 μL |
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| GLRX3-SGMS1-20-AQAQ | 20 (40 μL) | 200 μL |
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GLRX3 Gene Summary
This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Glutaredoxin 3
Chromosome: CHR10: 131934638 -131978646
Locus: 10q26.3
SGMS1 Gene Summary
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. [provided by RefSeq, Jul 2008]
Gene Name: Sphingomyelin Synthase 1
Chromosome: CHR10: 52065344 -52383737
Locus: 10q11.23
Gene Diseases
The GLRX3 SGMS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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