GLIS3-GOLM1 Fusion FISH Probe
The GLIS3-GOLM1 Fusion FISH Probe is used to confirm a fusion of the GLIS3 and GOLM1 genes. The fusion of the GLIS3 and GOLM1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLIS3-GOLM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-RERE | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-REOR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-REGO | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-REGR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-REAQ | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-ORRE | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-OROR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-ORGO | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GORE | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GOOR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GOGO | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GOGR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GRRE | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GROR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GRGO | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GRGR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-AQRE | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-AQOR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-AQGO | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-AQGR | 20 (40 μL) | 200 μL |
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| GLIS3-GOLM1-20-AQAQ | 20 (40 μL) | 200 μL |
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GOLM1 Gene Summary
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Golgi Membrane Protein 1
Chromosome: CHR9: 88641057 -88715116
Locus: 9q21.33
GLIS3 Gene Summary
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008]
Gene Name: GLIS Family Zinc Finger 3
Chromosome: CHR9: 3824127 -4300035
Locus: 9p24.2
Gene Diseases
The GLIS3 GOLM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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