GLE1-SLC27A4 Fusion FISH Probe
The GLE1-SLC27A4 Fusion FISH Probe is used to confirm a fusion of the GLE1 and SLC27A4 genes. The fusion of the GLE1 and SLC27A4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLE1-SLC27A4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-RERE | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-REOR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-REGO | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-REGR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-REAQ | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-ORRE | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-OROR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-ORGO | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GORE | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GOOR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GOGO | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GOGR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GRRE | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GROR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GRGO | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GRGR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-AQRE | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-AQOR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-AQGO | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-AQGR | 20 (40 μL) | 200 μL |
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| GLE1-SLC27A4-20-AQAQ | 20 (40 μL) | 200 μL |
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GLE1 Gene Summary
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: GLE1, RNA Export Mediator
Chromosome: CHR9: 131266970 -131304580
Locus: 9q34.11
SLC27A4 Gene Summary
This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
Gene Name: Solute Carrier Family 27 Member 4
Chromosome: CHR9: 131102838 -131123749
Locus: 9q34.11
Gene Diseases
The GLE1 SLC27A4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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