GLCCI1-DGKB Fusion FISH Probe
The GLCCI1-DGKB Fusion FISH Probe is used to confirm a fusion of the GLCCI1 and DGKB genes. The fusion of the GLCCI1 and DGKB genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GLCCI1-DGKB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-RERE | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-REOR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-REGO | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-REGR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-REAQ | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-ORRE | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-OROR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-ORGO | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-ORAQ | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GORE | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GOOR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GOGO | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GOGR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GOAQ | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GRRE | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GROR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GRGO | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GRGR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-GRAQ | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-AQRE | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-AQOR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-AQGO | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-AQGR | 20 (40 μL) | 200 μL |
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| GLCCI1-DGKB-20-AQAQ | 20 (40 μL) | 200 μL |
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DGKB Gene Summary
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Gene Name: Diacylglycerol Kinase Beta
Chromosome: CHR7: 14184673 -14881075
Locus: 7p21.2
GLCCI1 Gene Summary
This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients. [provided by RefSeq, Feb 2012]
Gene Name: Glucocorticoid Induced 1
Chromosome: CHR7: 8008422 -8128709
Locus: 7p21.3
Gene Diseases
The GLCCI1 DGKB Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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