GIT2-SLC2A13 Fusion FISH Probe
The GIT2-SLC2A13 Fusion FISH Probe is used to confirm a fusion of the GIT2 and SLC2A13 genes. The fusion of the GIT2 and SLC2A13 genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GIT2-SLC2A13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-RERE | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-REOR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-REGO | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-REGR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-REAQ | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-ORRE | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-OROR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-ORGO | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-ORAQ | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GORE | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GOOR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GOGO | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GOGR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GOAQ | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GRRE | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GROR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GRGO | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GRGR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-GRAQ | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-AQRE | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-AQOR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-AQGO | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-AQGR | 20 (40 μL) | 200 μL |
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| GIT2-SLC2A13-20-AQAQ | 20 (40 μL) | 200 μL |
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GIT2 Gene Summary
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]
Gene Name: GIT ArfGAP 2
Chromosome: CHR12: 110367606 -110434194
Locus: 12q24.11
SLC2A13 Gene Summary
The Solute Carrier Family 2 Member 13 (SLC2A13) gene is located on chr12 :40148822-40499661 at 12q12.
Gene Name: Solute Carrier Family 2 Member 13
Chromosome: CHR12: 40148822 -40499661
Locus: 12q12
Gene Diseases
The GIT2 SLC2A13 Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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