GIPR-PRR12 Fusion FISH Probe
The GIPR-PRR12 Fusion FISH Probe is used to confirm a fusion of the GIPR and PRR12 genes. The fusion of the GIPR and PRR12 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GIPR-PRR12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-RERE | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-REOR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-REGO | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-REGR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-REAQ | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-ORRE | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-OROR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-ORGO | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-ORAQ | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GORE | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GOOR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GOGO | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GOGR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GOAQ | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GRRE | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GROR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GRGO | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GRGR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-GRAQ | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-AQRE | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-AQOR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-AQGO | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-AQGR | 20 (40 μL) | 200 μL |
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| GIPR-PRR12-20-AQAQ | 20 (40 μL) | 200 μL |
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GIPR Gene Summary
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
Gene Name: Gastric Inhibitory Polypeptide Receptor
Chromosome: CHR19: 46171501 -46185717
Locus: 19q13.32
PRR12 Gene Summary
This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger, MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development. [provided by RefSeq, Jul 2016]
Gene Name: Proline Rich 12
Chromosome: CHR19: 50094911 -50129696
Locus: 19q13.33
Gene Diseases
The GIPR PRR12 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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