GIGYF2-SP2 Fusion FISH Probe
The GIGYF2-SP2 Fusion FISH Probe is used to confirm a fusion of the GIGYF2 and SP2 genes. The fusion of the GIGYF2 and SP2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GIGYF2-SP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-RERE | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-REOR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-REGO | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-REGR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-REAQ | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-ORRE | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-OROR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-ORGO | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GORE | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GOOR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GOGO | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GOGR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GRRE | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GROR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GRGO | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GRGR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-AQRE | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-AQOR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-AQGO | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-AQGR | 20 (40 μL) | 200 μL |
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| GIGYF2-SP2-20-AQAQ | 20 (40 μL) | 200 μL |
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SP2 Gene Summary
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
Gene Name: Sp2 Transcription Factor
Chromosome: CHR17: 45973515 -46006323
Locus: 17q21.32
GIGYF2 Gene Summary
This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: GRB10 Interacting GYF Protein 2
Chromosome: CHR2: 233562014 -233725289
Locus: 2q37.1
Gene Diseases
The GIGYF2 SP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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