GHR-GPR68 Fusion FISH Probe
The GHR-GPR68 Fusion FISH Probe is used to confirm a fusion of the GHR and GPR68 genes. The fusion of the GHR and GPR68 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GHR-GPR68-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-RERE | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-REOR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-REGO | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-REGR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-REAQ | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-ORRE | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-OROR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-ORGO | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-ORAQ | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GORE | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GOOR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GOGO | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GOGR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GOAQ | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GRRE | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GROR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GRGO | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GRGR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-GRAQ | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-AQRE | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-AQOR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-AQGO | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-AQGR | 20 (40 μL) | 200 μL |
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| GHR-GPR68-20-AQAQ | 20 (40 μL) | 200 μL |
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GHR Gene Summary
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
Gene Name: Growth Hormone Receptor
Chromosome: CHR5: 42423876 -42721980
Locus: 5p13.1-p12
GPR68 Gene Summary
The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
Gene Name: G Protein-coupled Receptor 68
Chromosome: CHR14: 91698875 -91720224
Locus: 14q32.11
Gene Diseases
The GHR GPR68 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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