GDI2-CPVL Fusion FISH Probe
The GDI2-CPVL Fusion FISH Probe is used to confirm a fusion of the GDI2 and CPVL genes. The fusion of the GDI2 and CPVL genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GDI2-CPVL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-RERE | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-REOR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-REGO | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-REGR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-REAQ | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-ORRE | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-OROR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-ORGO | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-ORAQ | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GORE | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GOOR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GOGO | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GOGR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GOAQ | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GRRE | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GROR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GRGO | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GRGR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-GRAQ | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-AQRE | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-AQOR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-AQGO | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-AQGR | 20 (40 μL) | 200 μL |
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| GDI2-CPVL-20-AQAQ | 20 (40 μL) | 200 μL |
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GDI2 Gene Summary
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: GDP Dissociation Inhibitor 2
Chromosome: CHR10: 5807185 -5855512
Locus: 10p15.1
CPVL Gene Summary
The protein encoded by this gene is a carboxypeptidase and bears strong sequence similarity to serine carboxypeptidases. Carboxypeptidases are a large class of proteases that act to cleave a single amino acid from the carboxy termini of proteins or peptides. The exact function of this protein, however, has not been determined. [provided by RefSeq, Jan 2017]
Gene Name: Carboxypeptidase, Vitellogenic Like
Chromosome: CHR7: 29035246 -29186153
Locus: 7p14.3
Gene Diseases
The GDI2 CPVL Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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