GCNT2-OSM Fusion FISH Probe
The GCNT2-OSM Fusion FISH Probe is used to confirm a fusion of the GCNT2 and OSM genes. The fusion of the GCNT2 and OSM genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GCNT2-OSM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-RERE | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-REOR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-REGO | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-REGR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-REAQ | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-ORRE | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-OROR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-ORGO | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-ORAQ | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GORE | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GOOR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GOGO | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GOGR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GOAQ | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GRRE | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GROR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GRGO | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GRGR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-GRAQ | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-AQRE | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-AQOR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-AQGO | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-AQGR | 20 (40 μL) | 200 μL |
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| GCNT2-OSM-20-AQAQ | 20 (40 μL) | 200 μL |
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GCNT2 Gene Summary
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Glucosaminyl (N-acetyl) Transferase 2, I-branching Enzyme (I Blood Group)
Chromosome: CHR6: 10521567 -10629601
Locus: 6p24.3-p24.2
OSM Gene Summary
This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Oncostatin M
Chromosome: CHR22: 30658818 -30662829
Locus: 22q12.2
Gene Diseases
The GCNT2 OSM Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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