GARS-HOXA13 Fusion FISH Probe
The GARS-HOXA13 Fusion FISH Probe is used to confirm a fusion of the GARS and HOXA13 genes. The fusion of the GARS and HOXA13 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GARS-HOXA13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-RERE | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-REOR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-REGO | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-REGR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-REAQ | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-ORRE | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-OROR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-ORGO | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-ORAQ | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GORE | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GOOR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GOGO | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GOGR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GOAQ | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GRRE | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GROR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GRGO | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GRGR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-GRAQ | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-AQRE | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-AQOR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-AQGO | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-AQGR | 20 (40 μL) | 200 μL |
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| GARS-HOXA13-20-AQAQ | 20 (40 μL) | 200 μL |
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GARS Gene Summary
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: Glycyl-tRNA Synthetase
Chromosome: CHR7: 30634180 -30673648
Locus: 7p14.3
HOXA13 Gene Summary
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Homeobox A13
Chromosome: CHR7: 27236498 -27239725
Locus: 7p15.2
Gene Diseases
The GARS HOXA13 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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