GANC-RORA Fusion FISH Probe
The GANC-RORA Fusion FISH Probe is used to confirm a fusion of the GANC and RORA genes. The fusion of the GANC and RORA genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GANC-RORA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-RERE | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-REOR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-REGO | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-REGR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-REAQ | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-ORRE | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-OROR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-ORGO | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-ORAQ | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GORE | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GOOR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GOGO | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GOGR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GOAQ | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GRRE | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GROR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GRGO | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GRGR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-GRAQ | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-AQRE | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-AQOR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-AQGO | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-AQGR | 20 (40 μL) | 200 μL |
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| GANC-RORA-20-AQAQ | 20 (40 μL) | 200 μL |
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GANC Gene Summary
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]
Gene Name: Glucosidase Alpha, Neutral C
Chromosome: CHR15: 42566365 -42645864
Locus: 15q15.1
RORA Gene Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Gene Name: RAR Related Orphan Receptor A
Chromosome: CHR15: 60780482 -61521502
Locus: 15q22.2
Gene Diseases
The GANC RORA Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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