GALNT14-NRXN1 Fusion FISH Probe
The GALNT14-NRXN1 Fusion FISH Probe is used to confirm a fusion of the GALNT14 and NRXN1 genes. The fusion of the GALNT14 and NRXN1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GALNT14-NRXN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| GALNT14-NRXN1-20-AQAQ | 20 (40 μL) | 200 μL |
|
NRXN1 Gene Summary
This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016]
Gene Name: Neurexin 1
Chromosome: CHR2: 50145642 -51259674
Locus: 2p16.3
GALNT14 Gene Summary
This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Alterations in this gene may play a role in cancer progression and response to chemotherapy. [provided by RefSeq, Jun 2016]
Gene Name: Polypeptide N-acetylgalactosaminyltransferase 14
Chromosome: CHR2: 31133332 -31361571
Locus: 2p23.1
Gene Diseases
The GALNT14 NRXN1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|