GALNT1-TAF4B Fusion FISH Probe
The GALNT1-TAF4B Fusion FISH Probe is used to confirm a fusion of the GALNT1 and TAF4B genes. The fusion of the GALNT1 and TAF4B genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GALNT1-TAF4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-RERE | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-REOR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-REGO | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-REGR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-REAQ | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-ORRE | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-OROR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-ORGO | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GORE | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GOOR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GOGO | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GOGR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GRRE | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GROR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GRGO | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GRGR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-AQRE | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-AQOR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-AQGO | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-AQGR | 20 (40 μL) | 200 μL |
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| GALNT1-TAF4B-20-AQAQ | 20 (40 μL) | 200 μL |
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GALNT1 Gene Summary
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. [provided by RefSeq, Jul 2008]
Gene Name: Polypeptide N-acetylgalactosaminyltransferase 1
Chromosome: CHR18: 33234532 -33291798
Locus: 18q12.2
TAF4B Gene Summary
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Name: TATA-box Binding Protein Associated Factor 4b
Chromosome: CHR18: 23806408 -23971650
Locus: 18q11.2
Gene Diseases
The GALNT1 TAF4B Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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