GABRA3-SARNP Fusion FISH Probe
The GABRA3-SARNP Fusion FISH Probe is used to confirm a fusion of the GABRA3 and SARNP genes. The fusion of the GABRA3 and SARNP genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GABRA3-SARNP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-RERE | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-REOR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-REGO | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-REGR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-REAQ | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-ORRE | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-OROR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-ORGO | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-ORAQ | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GORE | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GOOR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GOGO | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GOGR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GOAQ | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GRRE | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GROR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GRGO | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GRGR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-GRAQ | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-AQRE | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-AQOR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-AQGO | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-AQGR | 20 (40 μL) | 200 μL |
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| GABRA3-SARNP-20-AQAQ | 20 (40 μL) | 200 μL |
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GABRA3 Gene Summary
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Gamma-aminobutyric Acid Type A Receptor Alpha3 Subunit
Chromosome: CHRX: 151335633 -151619831
Locus: Xq28
SARNP Gene Summary
This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Gene Name: SAP Domain Containing Ribonucleoprotein
Chromosome: CHR12: 56146246 -56211540
Locus: 12q13.2
Gene Diseases
The GABRA3 SARNP Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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