GABPB2-MLLT11 Fusion FISH Probe
The GABPB2-MLLT11 Fusion FISH Probe is used to confirm a fusion of the GABPB2 and MLLT11 genes. The fusion of the GABPB2 and MLLT11 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GABPB2-MLLT11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-RERE | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-REOR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-REGO | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-REGR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-REAQ | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-ORRE | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-OROR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-ORGO | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-ORAQ | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GORE | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GOOR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GOGO | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GOGR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GOAQ | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GRRE | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GROR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GRGO | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GRGR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-GRAQ | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-AQRE | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-AQOR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-AQGO | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-AQGR | 20 (40 μL) | 200 μL |
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| GABPB2-MLLT11-20-AQAQ | 20 (40 μL) | 200 μL |
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MLLT11 Gene Summary
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]
Gene Name: MLLT11, Transcription Factor 7 Cofactor
Chromosome: CHR1: 151032150 -151040973
Locus: 1q21.3
GABPB2 Gene Summary
The GA Binding Protein Transcription Factor Beta Subunit 2 (GABPB2) gene is located on chr1 :151043079-151091007 at 1q21.3.
Gene Name: GA Binding Protein Transcription Factor Beta Subunit 2
Chromosome: CHR1: 151043079 -151091007
Locus: 1q21.3
Gene Diseases
The GABPB2 MLLT11 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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