GABPB1-TRPM7 Fusion FISH Probe
The GABPB1-TRPM7 Fusion FISH Probe is used to confirm a fusion of the GABPB1 and TRPM7 genes. The fusion of the GABPB1 and TRPM7 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GABPB1-TRPM7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-RERE | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-REOR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-REGO | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-REGR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-REAQ | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-ORRE | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-OROR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-ORGO | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-ORAQ | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GORE | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GOOR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GOGO | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GOGR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GOAQ | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GRRE | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GROR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GRGO | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GRGR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-GRAQ | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-AQRE | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-AQOR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-AQGO | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-AQGR | 20 (40 μL) | 200 μL |
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| GABPB1-TRPM7-20-AQAQ | 20 (40 μL) | 200 μL |
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GABPB1 Gene Summary
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: GA Binding Protein Transcription Factor Beta Subunit 1
Chromosome: CHR15: 50569388 -50647605
Locus: 15q21.2
TRPM7 Gene Summary
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
Gene Name: Transient Receptor Potential Cation Channel Subfamily M Member 7
Chromosome: CHR15: 50849351 -50979012
Locus: 15q21.2
Gene Diseases
The GABPB1 TRPM7 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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