GABPA-JAM2 Fusion FISH Probe
The GABPA-JAM2 Fusion FISH Probe is used to confirm a fusion of the GABPA and JAM2 genes. The fusion of the GABPA and JAM2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GABPA-JAM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-RERE | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-REOR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-REGO | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-REGR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-REAQ | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-ORRE | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-OROR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-ORGO | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GORE | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GOOR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GOGO | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GOGR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GRRE | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GROR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GRGO | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GRGR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-AQRE | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-AQOR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-AQGO | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-AQGR | 20 (40 μL) | 200 μL |
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| GABPA-JAM2-20-AQAQ | 20 (40 μL) | 200 μL |
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GABPA Gene Summary
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: GA Binding Protein Transcription Factor Alpha Subunit
Chromosome: CHR21: 27107257 -27144771
Locus: 21q21.3
JAM2 Gene Summary
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Junctional Adhesion Molecule 2
Chromosome: CHR21: 27011588 -27087235
Locus: 21q21.3
Gene Diseases
The GABPA JAM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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