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GAB2-FGF7 Fusion FISH Probe

The GAB2-FGF7 Fusion FISH Probe is used to confirm a fusion of the GAB2 and FGF7 genes. The fusion of the GAB2 and FGF7 genes has been associated with Skin Cutaneous Melanoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GAB2-FGF7-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GAB2-FGF7-20-RERE 20 (40 μL) 200 μL
GAB2-FGF7-20-REOR 20 (40 μL) 200 μL
GAB2-FGF7-20-REGO 20 (40 μL) 200 μL
GAB2-FGF7-20-REGR 20 (40 μL) 200 μL
GAB2-FGF7-20-REAQ 20 (40 μL) 200 μL
GAB2-FGF7-20-ORRE 20 (40 μL) 200 μL
GAB2-FGF7-20-OROR 20 (40 μL) 200 μL
GAB2-FGF7-20-ORGO 20 (40 μL) 200 μL
GAB2-FGF7-20-ORAQ 20 (40 μL) 200 μL
GAB2-FGF7-20-GORE 20 (40 μL) 200 μL
GAB2-FGF7-20-GOOR 20 (40 μL) 200 μL
GAB2-FGF7-20-GOGO 20 (40 μL) 200 μL
GAB2-FGF7-20-GOGR 20 (40 μL) 200 μL
GAB2-FGF7-20-GOAQ 20 (40 μL) 200 μL
GAB2-FGF7-20-GRRE 20 (40 μL) 200 μL
GAB2-FGF7-20-GROR 20 (40 μL) 200 μL
GAB2-FGF7-20-GRGO 20 (40 μL) 200 μL
GAB2-FGF7-20-GRGR 20 (40 μL) 200 μL
GAB2-FGF7-20-GRAQ 20 (40 μL) 200 μL
GAB2-FGF7-20-AQRE 20 (40 μL) 200 μL
GAB2-FGF7-20-AQOR 20 (40 μL) 200 μL
GAB2-FGF7-20-AQGO 20 (40 μL) 200 μL
GAB2-FGF7-20-AQGR 20 (40 μL) 200 μL
GAB2-FGF7-20-AQAQ 20 (40 μL) 200 μL

FGF7 Gene Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]

Gene Name: Fibroblast Growth Factor 7

Chromosome: CHR15: 49715374 -49779523

Locus: 15q21.2

GAB2 Gene Summary

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]

Gene Name: GRB2 Associated Binding Protein 2

Chromosome: CHR11: 77926335 -78128868

Locus: 11q14.1

Gene Diseases

The GAB2 FGF7 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.