G6PD-STAT6 Fusion FISH Probe
The G6PD-STAT6 Fusion FISH Probe is used to confirm a fusion of the G6PD and STAT6 genes. The fusion of the G6PD and STAT6 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| G6PD-STAT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-RERE | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-REOR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-REGO | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-REGR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-REAQ | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-ORRE | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-OROR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-ORGO | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GORE | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GOOR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GOGO | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GOGR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GRRE | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GROR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GRGO | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GRGR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-AQRE | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-AQOR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-AQGO | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-AQGR | 20 (40 μL) | 200 μL |
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| G6PD-STAT6-20-AQAQ | 20 (40 μL) | 200 μL |
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G6PD Gene Summary
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Glucose-6-phosphate Dehydrogenase
Chromosome: CHRX: 153759605 -153775787
Locus: Xq28
STAT6 Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Signal Transducer And Activator Of Transcription 6
Chromosome: CHR12: 57489186 -57505196
Locus: 12q13.3
Gene Diseases
The G6PD STAT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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