FZD6-SDCCAG8 Fusion FISH Probe
The FZD6-SDCCAG8 Fusion FISH Probe is used to confirm a fusion of the FZD6 and SDCCAG8 genes. The fusion of the FZD6 and SDCCAG8 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FZD6-SDCCAG8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-RERE | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-REOR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-REGO | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-REGR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-REAQ | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-ORRE | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-OROR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-ORGO | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-ORAQ | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GORE | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GOOR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GOGO | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GOGR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GOAQ | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GRRE | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GROR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GRGO | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GRGR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-GRAQ | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-AQRE | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-AQOR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-AQGO | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-AQGR | 20 (40 μL) | 200 μL |
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| FZD6-SDCCAG8-20-AQAQ | 20 (40 μL) | 200 μL |
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FZD6 Gene Summary
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]
Gene Name: Frizzled Class Receptor 6
Chromosome: CHR8: 104310660 -104345094
Locus: 8q22.3
SDCCAG8 Gene Summary
This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]
Gene Name: Serologically Defined Colon Cancer Antigen 8
Chromosome: CHR1: 243419306 -243663393
Locus: 1q43-q44
Gene Diseases
The FZD6 SDCCAG8 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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