FXYD6-ZEB2 Fusion FISH Probe
The FXYD6-ZEB2 Fusion FISH Probe is used to confirm a fusion of the FXYD6 and ZEB2 genes. The fusion of the FXYD6 and ZEB2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FXYD6-ZEB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-RERE | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-REOR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-REGO | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-REGR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-REAQ | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-ORRE | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-OROR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-ORGO | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GORE | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GOOR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GOGO | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GOGR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GRRE | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GROR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GRGO | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GRGR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-AQRE | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-AQOR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-AQGO | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-AQGR | 20 (40 μL) | 200 μL |
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| FXYD6-ZEB2-20-AQAQ | 20 (40 μL) | 200 μL |
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ZEB2 Gene Summary
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
Gene Name: Zinc Finger E-box Binding Homeobox 2
Chromosome: CHR2: 145141941 -145277958
Locus: 2q22.3
FXYD6 Gene Summary
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011]
Gene Name: FXYD Domain Containing Ion Transport Regulator 6
Chromosome: CHR11: 117707690 -117748201
Locus: 11q23.3
Gene Diseases
The FXYD6 ZEB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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