FXYD6-CD3G Fusion FISH Probe
The FXYD6-CD3G Fusion FISH Probe is used to confirm a fusion of the FXYD6 and CD3G genes. The fusion of the FXYD6 and CD3G genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FXYD6-CD3G-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-RERE | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-REOR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-REGO | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-REGR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-REAQ | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-ORRE | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-OROR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-ORGO | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-ORAQ | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GORE | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GOOR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GOGO | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GOGR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GOAQ | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GRRE | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GROR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GRGO | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GRGR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-GRAQ | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-AQRE | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-AQOR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-AQGO | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-AQGR | 20 (40 μL) | 200 μL |
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| FXYD6-CD3G-20-AQAQ | 20 (40 μL) | 200 μL |
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CD3G Gene Summary
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]
Gene Name: CD3g Molecule
Chromosome: CHR11: 118215058 -118224497
Locus: 11q23.3
FXYD6 Gene Summary
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011]
Gene Name: FXYD Domain Containing Ion Transport Regulator 6
Chromosome: CHR11: 117707690 -117748201
Locus: 11q23.3
Gene Diseases
The FXYD6 CD3G Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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