FXR1-FGF10 Fusion FISH Probe
The FXR1-FGF10 Fusion FISH Probe is used to confirm a fusion of the FXR1 and FGF10 genes. The fusion of the FXR1 and FGF10 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FXR1-FGF10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FXR1-FGF10-20-AQAQ | 20 (40 μL) | 200 μL |
|
FGF10 Gene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008]
Gene Name: Fibroblast Growth Factor 10
Chromosome: CHR5: 44305096 -44388784
Locus: 5p12
FXR1 Gene Summary
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: FMR1 Autosomal Homolog 1
Chromosome: CHR3: 180630233 -180700539
Locus: 3q26.33
Gene Diseases
The FXR1 FGF10 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|