FUK-ABCB5 Fusion FISH Probe
The FUK-ABCB5 Fusion FISH Probe is used to confirm a fusion of the FUK and ABCB5 genes. The fusion of the FUK and ABCB5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FUK-ABCB5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-RERE | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-REOR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-REGO | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-REGR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-REAQ | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-ORRE | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-OROR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-ORGO | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-ORAQ | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GORE | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GOOR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GOGO | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GOGR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GOAQ | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GRRE | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GROR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GRGO | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GRGR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-GRAQ | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-AQRE | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-AQOR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-AQGO | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-AQGR | 20 (40 μL) | 200 μL |
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| FUK-ABCB5-20-AQAQ | 20 (40 μL) | 200 μL |
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FUK Gene Summary
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]
Gene Name: Fucokinase
Chromosome: CHR16: 70488497 -70514177
Locus: 16q22.1
ABCB5 Gene Summary
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
Gene Name: ATP Binding Cassette Subfamily B Member 5
Chromosome: CHR7: 20655244 -20796637
Locus: 7p21.1
Gene Diseases
The FUK ABCB5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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