FTSJD2-GPX6 Fusion FISH Probe
The FTSJD2-GPX6 Fusion FISH Probe is used to confirm a fusion of the FTSJD2 and GPX6 genes. The fusion of the FTSJD2 and GPX6 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FTSJD2-GPX6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-RERE | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-REOR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-REGO | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-REGR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-REAQ | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-ORRE | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-OROR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-ORGO | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-ORAQ | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GORE | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GOOR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GOGO | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GOGR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GOAQ | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GRRE | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GROR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GRGO | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GRGR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-GRAQ | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-AQRE | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-AQOR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-AQGO | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-AQGR | 20 (40 μL) | 200 μL |
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| FTSJD2-GPX6-20-AQAQ | 20 (40 μL) | 200 μL |
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GPX6 Gene Summary
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. Expression of this gene has been observed in embryos and olfactory epithelium; however, the exact function of this gene is not known. This isozyme is a selenoprotein in humans, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The orthologs of this gene in mouse and rat (and some other species) contain a cysteine (Cys) residue in place of the Sec residue, and their corresponding mRNAs lack SECIS element. [provided by RefSeq, Jul 2017]
Gene Name: Glutathione Peroxidase 6
Chromosome: CHR6: 28471072 -28483570
Locus: 6p22.1
Gene Diseases
The FTSJD2 GPX6 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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