FTO-ZNF536 Fusion FISH Probe
The FTO-ZNF536 Fusion FISH Probe is used to confirm a fusion of the FTO and ZNF536 genes. The fusion of the FTO and ZNF536 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FTO-ZNF536-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-RERE | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-REOR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-REGO | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-REGR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-REAQ | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-ORRE | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-OROR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-ORGO | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-ORAQ | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GORE | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GOOR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GOGO | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GOGR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GOAQ | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GRRE | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GROR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GRGO | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GRGR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-GRAQ | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-AQRE | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-AQOR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-AQGO | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-AQGR | 20 (40 μL) | 200 μL |
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| FTO-ZNF536-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF536 Gene Summary
The protein encoded by this gene is a highly conserved zinc finger protein. The encoded protein is most abundant in brain, where it negatively regulates neuronal differentiation. [provided by RefSeq, Sep 2015]
Gene Name: Zinc Finger Protein 536
Chromosome: CHR19: 30863327 -31048965
Locus: 19q12
FTO Gene Summary
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Gene Name: FTO, Alpha-ketoglutarate Dependent Dioxygenase
Chromosome: CHR16: 53737874 -54148379
Locus: 16q12.2
Gene Diseases
The FTO ZNF536 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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