FTL-FADS2 Fusion FISH Probe
The FTL-FADS2 Fusion FISH Probe is used to confirm a fusion of the FTL and FADS2 genes. The fusion of the FTL and FADS2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FTL-FADS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-RERE | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-REOR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-REGO | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-REGR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-REAQ | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-ORRE | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-OROR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-ORGO | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GORE | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GOOR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GOGO | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GOGR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GRRE | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GROR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GRGO | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GRGR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-AQRE | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-AQOR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-AQGO | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-AQGR | 20 (40 μL) | 200 μL |
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| FTL-FADS2-20-AQAQ | 20 (40 μL) | 200 μL |
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FTL Gene Summary
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
Gene Name: Ferritin Light Chain
Chromosome: CHR19: 49468565 -49470136
Locus: 19q13.33
FADS2 Gene Summary
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Name: Fatty Acid Desaturase 2
Chromosome: CHR11: 61595712 -61634825
Locus: 11q12.2
Gene Diseases
The FTL FADS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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