FRYL-UNC13B Fusion FISH Probe
The FRYL-UNC13B Fusion FISH Probe is used to confirm a fusion of the FRYL and UNC13B genes. The fusion of the FRYL and UNC13B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRYL-UNC13B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-RERE | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-REOR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-REGO | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-REGR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-REAQ | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-ORRE | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-OROR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-ORGO | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GORE | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GOOR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GOGO | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GOGR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GRRE | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GROR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GRGO | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GRGR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-AQRE | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-AQOR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-AQGO | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-AQGR | 20 (40 μL) | 200 μL |
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| FRYL-UNC13B-20-AQAQ | 20 (40 μL) | 200 μL |
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UNC13B Gene Summary
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Gene Name: Unc-13 Homolog B
Chromosome: CHR9: 35161988 -35405332
Locus: 9p13.3
FRYL Gene Summary
The FRY Like Transcription Coactivator (FRYL) gene is located on chr4 :48499379-48782316 at 4p11.
Gene Name: FRY Like Transcription Coactivator
Chromosome: CHR4: 48499379 -48782316
Locus: 4p11
Gene Diseases
The FRYL UNC13B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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