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FRS2-PTPRR Fusion FISH Probe

The FRS2-PTPRR Fusion FISH Probe is used to confirm a fusion of the FRS2 and PTPRR genes. The fusion of the FRS2 and PTPRR genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FRS2-PTPRR-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FRS2-PTPRR-20-RERE 20 (40 μL) 200 μL
FRS2-PTPRR-20-REOR 20 (40 μL) 200 μL
FRS2-PTPRR-20-REGO 20 (40 μL) 200 μL
FRS2-PTPRR-20-REGR 20 (40 μL) 200 μL
FRS2-PTPRR-20-REAQ 20 (40 μL) 200 μL
FRS2-PTPRR-20-ORRE 20 (40 μL) 200 μL
FRS2-PTPRR-20-OROR 20 (40 μL) 200 μL
FRS2-PTPRR-20-ORGO 20 (40 μL) 200 μL
FRS2-PTPRR-20-ORAQ 20 (40 μL) 200 μL
FRS2-PTPRR-20-GORE 20 (40 μL) 200 μL
FRS2-PTPRR-20-GOOR 20 (40 μL) 200 μL
FRS2-PTPRR-20-GOGO 20 (40 μL) 200 μL
FRS2-PTPRR-20-GOGR 20 (40 μL) 200 μL
FRS2-PTPRR-20-GOAQ 20 (40 μL) 200 μL
FRS2-PTPRR-20-GRRE 20 (40 μL) 200 μL
FRS2-PTPRR-20-GROR 20 (40 μL) 200 μL
FRS2-PTPRR-20-GRGO 20 (40 μL) 200 μL
FRS2-PTPRR-20-GRGR 20 (40 μL) 200 μL
FRS2-PTPRR-20-GRAQ 20 (40 μL) 200 μL
FRS2-PTPRR-20-AQRE 20 (40 μL) 200 μL
FRS2-PTPRR-20-AQOR 20 (40 μL) 200 μL
FRS2-PTPRR-20-AQGO 20 (40 μL) 200 μL
FRS2-PTPRR-20-AQGR 20 (40 μL) 200 μL
FRS2-PTPRR-20-AQAQ 20 (40 μL) 200 μL

PTPRR Gene Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]

Gene Name: Protein Tyrosine Phosphatase, Receptor Type R

Chromosome: CHR12: 71031852 -71314584

Locus: 12q15

FRS2 Gene Summary

The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.

Gene Name: Fibroblast Growth Factor Receptor Substrate 2

Chromosome: CHR12: 69864128 -69973562

Locus: 12q15

Gene Diseases

The FRS2 PTPRR Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.