FRS2-MSRB3 Fusion FISH Probe
The FRS2-MSRB3 Fusion FISH Probe is used to confirm a fusion of the FRS2 and MSRB3 genes. The fusion of the FRS2 and MSRB3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRS2-MSRB3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-RERE | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-REOR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-REGO | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-REGR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-REAQ | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-ORRE | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-OROR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-ORGO | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GORE | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GOOR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GOGO | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GOGR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GRRE | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GROR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GRGO | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GRGR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-AQRE | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-AQOR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-AQGO | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-AQGR | 20 (40 μL) | 200 μL |
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| FRS2-MSRB3-20-AQAQ | 20 (40 μL) | 200 μL |
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FRS2 Gene Summary
The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.
Gene Name: Fibroblast Growth Factor Receptor Substrate 2
Chromosome: CHR12: 69864128 -69973562
Locus: 12q15
MSRB3 Gene Summary
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]
Gene Name: Methionine Sulfoxide Reductase B3
Chromosome: CHR12: 65672422 -65860687
Locus: 12q14.3
Gene Diseases
The FRS2 MSRB3 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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