FRS2-MMP19 Fusion FISH Probe
The FRS2-MMP19 Fusion FISH Probe is used to confirm a fusion of the FRS2 and MMP19 genes. The fusion of the FRS2 and MMP19 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRS2-MMP19-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-RERE | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-REOR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-REGO | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-REGR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-REAQ | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-ORRE | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-OROR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-ORGO | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GORE | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GOOR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GOGO | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GOGR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GRRE | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GROR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GRGO | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GRGR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-AQRE | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-AQOR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-AQGO | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-AQGR | 20 (40 μL) | 200 μL |
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| FRS2-MMP19-20-AQAQ | 20 (40 μL) | 200 μL |
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MMP19 Gene Summary
This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Gene Name: Matrix Metallopeptidase 19
Chromosome: CHR12: 56229213 -56236735
Locus: 12q13.2
FRS2 Gene Summary
The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.
Gene Name: Fibroblast Growth Factor Receptor Substrate 2
Chromosome: CHR12: 69864128 -69973562
Locus: 12q15
Gene Diseases
The FRS2 MMP19 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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