FRS2-LEMD3 Fusion FISH Probe
The FRS2-LEMD3 Fusion FISH Probe is used to confirm a fusion of the FRS2 and LEMD3 genes. The fusion of the FRS2 and LEMD3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRS2-LEMD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-RERE | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-REOR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-REGO | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-REGR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-REAQ | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-ORRE | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-OROR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-ORGO | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GORE | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GOOR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GOGO | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GOGR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GRRE | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GROR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GRGO | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GRGR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-AQRE | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-AQOR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-AQGO | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-AQGR | 20 (40 μL) | 200 μL |
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| FRS2-LEMD3-20-AQAQ | 20 (40 μL) | 200 μL |
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FRS2 Gene Summary
The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.
Gene Name: Fibroblast Growth Factor Receptor Substrate 2
Chromosome: CHR12: 69864128 -69973562
Locus: 12q15
LEMD3 Gene Summary
This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
Gene Name: LEM Domain Containing 3
Chromosome: CHR12: 65563350 -65642141
Locus: 12q14.3
Gene Diseases
The FRS2 LEMD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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