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FRS2-DRAM1 Fusion FISH Probe

The FRS2-DRAM1 Fusion FISH Probe is used to confirm a fusion of the FRS2 and DRAM1 genes. The fusion of the FRS2 and DRAM1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FRS2-DRAM1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FRS2-DRAM1-20-RERE 20 (40 μL) 200 μL
FRS2-DRAM1-20-REOR 20 (40 μL) 200 μL
FRS2-DRAM1-20-REGO 20 (40 μL) 200 μL
FRS2-DRAM1-20-REGR 20 (40 μL) 200 μL
FRS2-DRAM1-20-REAQ 20 (40 μL) 200 μL
FRS2-DRAM1-20-ORRE 20 (40 μL) 200 μL
FRS2-DRAM1-20-OROR 20 (40 μL) 200 μL
FRS2-DRAM1-20-ORGO 20 (40 μL) 200 μL
FRS2-DRAM1-20-ORAQ 20 (40 μL) 200 μL
FRS2-DRAM1-20-GORE 20 (40 μL) 200 μL
FRS2-DRAM1-20-GOOR 20 (40 μL) 200 μL
FRS2-DRAM1-20-GOGO 20 (40 μL) 200 μL
FRS2-DRAM1-20-GOGR 20 (40 μL) 200 μL
FRS2-DRAM1-20-GOAQ 20 (40 μL) 200 μL
FRS2-DRAM1-20-GRRE 20 (40 μL) 200 μL
FRS2-DRAM1-20-GROR 20 (40 μL) 200 μL
FRS2-DRAM1-20-GRGO 20 (40 μL) 200 μL
FRS2-DRAM1-20-GRGR 20 (40 μL) 200 μL
FRS2-DRAM1-20-GRAQ 20 (40 μL) 200 μL
FRS2-DRAM1-20-AQRE 20 (40 μL) 200 μL
FRS2-DRAM1-20-AQOR 20 (40 μL) 200 μL
FRS2-DRAM1-20-AQGO 20 (40 μL) 200 μL
FRS2-DRAM1-20-AQGR 20 (40 μL) 200 μL
FRS2-DRAM1-20-AQAQ 20 (40 μL) 200 μL

FRS2 Gene Summary

The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.

Gene Name: Fibroblast Growth Factor Receptor Substrate 2

Chromosome: CHR12: 69864128 -69973562

Locus: 12q15

DRAM1 Gene Summary

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]

Gene Name: DNA Damage Regulated Autophagy Modulator 1

Chromosome: CHR12: 102271104 -102317401

Locus: 12q23.2

Gene Diseases

The FRS2 DRAM1 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.