FRS2-DNM2 Fusion FISH Probe
The FRS2-DNM2 Fusion FISH Probe is used to confirm a fusion of the FRS2 and DNM2 genes. The fusion of the FRS2 and DNM2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRS2-DNM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-RERE | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-REOR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-REGO | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-REGR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-REAQ | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-ORRE | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-OROR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-ORGO | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GORE | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GOOR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GOGO | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GOGR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GRRE | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GROR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GRGO | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GRGR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-AQRE | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-AQOR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-AQGO | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-AQGR | 20 (40 μL) | 200 μL |
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| FRS2-DNM2-20-AQAQ | 20 (40 μL) | 200 μL |
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DNM2 Gene Summary
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
Gene Name: Dynamin 2
Chromosome: CHR19: 10828728 -10942586
Locus: 19p13.2
FRS2 Gene Summary
The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.
Gene Name: Fibroblast Growth Factor Receptor Substrate 2
Chromosome: CHR12: 69864128 -69973562
Locus: 12q15
Gene Diseases
The FRS2 DNM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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