FRS2-AKAP12 Fusion FISH Probe
The FRS2-AKAP12 Fusion FISH Probe is used to confirm a fusion of the FRS2 and AKAP12 genes. The fusion of the FRS2 and AKAP12 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRS2-AKAP12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-RERE | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-REOR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-REGO | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-REGR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-REAQ | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-ORRE | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-OROR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-ORGO | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GORE | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GOOR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GOGO | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GOGR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GRRE | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GROR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GRGO | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GRGR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-AQRE | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-AQOR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-AQGO | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-AQGR | 20 (40 μL) | 200 μL |
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| FRS2-AKAP12-20-AQAQ | 20 (40 μL) | 200 μL |
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AKAP12 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: A-kinase Anchoring Protein 12
Chromosome: CHR6: 151561133 -151679694
Locus: 6q25.1
FRS2 Gene Summary
The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.
Gene Name: Fibroblast Growth Factor Receptor Substrate 2
Chromosome: CHR12: 69864128 -69973562
Locus: 12q15
Gene Diseases
The FRS2 AKAP12 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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