FRMD8-DPF2 Fusion FISH Probe
The FRMD8-DPF2 Fusion FISH Probe is used to confirm a fusion of the FRMD8 and DPF2 genes. The fusion of the FRMD8 and DPF2 genes has been associated with Lung Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRMD8-DPF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-RERE | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-REOR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-REGO | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-REGR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-REAQ | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-ORRE | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-OROR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-ORGO | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GORE | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GOOR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GOGO | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GOGR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GRRE | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GROR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GRGO | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GRGR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-AQRE | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-AQOR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-AQGO | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-AQGR | 20 (40 μL) | 200 μL |
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| FRMD8-DPF2-20-AQAQ | 20 (40 μL) | 200 μL |
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DPF2 Gene Summary
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
Gene Name: Double PHD Fingers 2
Chromosome: CHR11: 65101224 -65120451
Locus: 11q13.1
FRMD8 Gene Summary
The FERM Domain Containing 8 (FRMD8) gene is located on chr11 :65154040-65180995 at 11q13.1.
Gene Name: FERM Domain Containing 8
Chromosome: CHR11: 65154040 -65180995
Locus: 11q13.1
Gene Diseases
The FRMD8 DPF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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