FRMD5-ARNT2 Fusion FISH Probe
The FRMD5-ARNT2 Fusion FISH Probe is used to confirm a fusion of the FRMD5 and ARNT2 genes. The fusion of the FRMD5 and ARNT2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRMD5-ARNT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-RERE | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-REOR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-REGO | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-REGR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-REAQ | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-ORRE | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-OROR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-ORGO | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GORE | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GOOR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GOGO | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GOGR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GRRE | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GROR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GRGO | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GRGR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-AQRE | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-AQOR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-AQGO | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-AQGR | 20 (40 μL) | 200 μL |
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| FRMD5-ARNT2-20-AQAQ | 20 (40 μL) | 200 μL |
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ARNT2 Gene Summary
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]
Gene Name: Aryl Hydrocarbon Receptor Nuclear Translocator 2
Chromosome: CHR15: 80696691 -80890277
Locus: 15q25.1
FRMD5 Gene Summary
The FERM Domain Containing 5 (FRMD5) gene is located on chr15 :44165729-44487429 at 15q15.3.
Gene Name: FERM Domain Containing 5
Chromosome: CHR15: 44165729 -44487429
Locus: 15q15.3
Gene Diseases
The FRMD5 ARNT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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