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FRMD4A-TMEM45B Fusion FISH Probe

The FRMD4A-TMEM45B Fusion FISH Probe is used to confirm a fusion of the FRMD4A and TMEM45B genes. The fusion of the FRMD4A and TMEM45B genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FRMD4A-TMEM45B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-RERE 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-REOR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-REGO 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-REGR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-REAQ 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-ORRE 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-OROR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-ORGO 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-ORAQ 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GORE 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GOOR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GOGO 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GOGR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GOAQ 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GRRE 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GROR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GRGO 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GRGR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-GRAQ 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-AQRE 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-AQOR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-AQGO 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-AQGR 20 (40 μL) 200 μL
FRMD4A-TMEM45B-20-AQAQ 20 (40 μL) 200 μL

FRMD4A Gene Summary

This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Gene Name: FERM Domain Containing 4A

Chromosome: CHR10: 13685705 -14372866

Locus: 10p13

TMEM45B Gene Summary

The Transmembrane Protein 45B (TMEM45B) gene is located on chr11 :129685740-129729898 at 11q24.3.

Gene Name: Transmembrane Protein 45B

Chromosome: CHR11: 129685740 -129729898

Locus: 11q24.3

Gene Diseases

The FRMD4A TMEM45B Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.