FRMD4A-TMEM45B Fusion FISH Probe
The FRMD4A-TMEM45B Fusion FISH Probe is used to confirm a fusion of the FRMD4A and TMEM45B genes. The fusion of the FRMD4A and TMEM45B genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRMD4A-TMEM45B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-RERE | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-REOR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-REGO | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-REGR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-REAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-ORRE | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-OROR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-ORGO | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GORE | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GOOR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GOGO | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GOGR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GRRE | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GROR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GRGO | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GRGR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-AQRE | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-AQOR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-AQGO | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-AQGR | 20 (40 μL) | 200 μL |
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| FRMD4A-TMEM45B-20-AQAQ | 20 (40 μL) | 200 μL |
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FRMD4A Gene Summary
This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: FERM Domain Containing 4A
Chromosome: CHR10: 13685705 -14372866
Locus: 10p13
TMEM45B Gene Summary
The Transmembrane Protein 45B (TMEM45B) gene is located on chr11 :129685740-129729898 at 11q24.3.
Gene Name: Transmembrane Protein 45B
Chromosome: CHR11: 129685740 -129729898
Locus: 11q24.3
Gene Diseases
The FRMD4A TMEM45B Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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