FRMD4A-OR13A1 Fusion FISH Probe
The FRMD4A-OR13A1 Fusion FISH Probe is used to confirm a fusion of the FRMD4A and OR13A1 genes. The fusion of the FRMD4A and OR13A1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRMD4A-OR13A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-RERE | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-REOR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-REGO | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-REGR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-REAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-ORRE | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-OROR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-ORGO | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GORE | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GOOR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GOGO | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GOGR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GRRE | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GROR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GRGO | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GRGR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-AQRE | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-AQOR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-AQGO | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-AQGR | 20 (40 μL) | 200 μL |
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| FRMD4A-OR13A1-20-AQAQ | 20 (40 μL) | 200 μL |
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FRMD4A Gene Summary
This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: FERM Domain Containing 4A
Chromosome: CHR10: 13685705 -14372866
Locus: 10p13
OR13A1 Gene Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Name: Olfactory Receptor Family 13 Subfamily A Member 1
Chromosome: CHR10: 45798101 -45811056
Locus: 10q11.21
Gene Diseases
The FRMD4A OR13A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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